他最小的儿子贝尔纳多城堡Valerio六岁时去世。Valerio和他的兄弟作为的贵族家庭。虽然被他学习文学专业的初衷,他画的亲和力。这是指出他的顾客,他安排他的学徒多梅尼科Fiasella。之后,他研究了乔凡尼安德里亚·德·法拉利。寻求新的灵感,他前往米兰和帕尔玛,可能在1640年和1645年之间。在米兰他欣赏卡米洛•Proccacini的工作。从那里,他前往帕尔玛.

他擅长绘画战争场面。他也是相当多产的短暂的生命里,他在热那亚。他画的强奸sabine,现在宫殿Brignole,热那亚和装饰的圆顶教堂del Vastato德拉桑蒂西马·阿努佳塔在同一个城市。弗朗西斯科·玛丽亚Balbi家,他勾结了quadraturista从博洛尼亚,安德里亚Sghizzi壁画的宫殿。

在他的作品中他是被他的崇拜者视为结合之火丁托列托与一般的风格保罗·委罗内塞。加莱影响年轻的工作多梅尼科Piola。他还羡慕的工作安东尼·范·戴克在热那亚,他花了很长时间,其绘画可以看到整个城市。在他的学生中有巴特洛Biscaino,乔凡尼保罗Cervetto和斯特凡诺马尼亚斯科领导的父亲亚历山德罗).

He was the youngest son of Bernardo Castello, who died when Valerio was six years old. Valerio and his brothers were attached to the noble family of Torquato. While it had been the original intention for him to study a literate profession, he showed an affinity to drawing. This was noted by his patrons, who arranged his apprenticeship with Domenico Fiasella. Later he studied with Giovanni Andrea de’ Ferrari. To seek new inspiration, he travelled to Milan and then to Parma, probably between 1640 and 1645. In Milan he admired the work of Camillo Proccacini. From there, he traveled toParma.^[1]

He excelled in painting battle-scenes. He was also quite prolific within Genoa during his short life. He painted the Rape of the Sabines, now in the Palazzo Brignole, Genoa, and decorated the cupola of the Basilica della Santissima Annunziata del Vastato in the same city. For the house of Francesco Maria Balbi, he collaborated with the quadraturista from Bologna,Andrea Sghizzi to fresco the palace.

In his works he is regarded by his admirers as combining the fire of Tintoretto with the general style of Paolo Veronese. Castello influenced the work of young Domenico Piola. He also admired the work of Antony van Dyck, who had spent a long time in Genoa and whose paintings could be seen all over the city. Among his pupils were Bartolomeo Biscaino, Giovanni Paolo Cervetto, and Stefano Magnasco (the father of Alessandro).